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Thymidine labeling index

WebbThe results of flow cytometry were compared with the tritiated thymidine labeling index (TLI) in 314 tumors studied in one laboratory and 163 tumors f We use cookies to enhance your experience on our website.By continuing to … Webb3H-thymidine labeling index (TLI) was one of the first markers of proliferation used in breast cancer. The number of cells undergoing DNA synthesis is measured by 3 H …

Prognostic and predictive value of thymidine labelling index

WebbThe DNA labelling index (LI), representing the fraction of S-phase cells, was studied in 76 patients operated on for breast cancer from 1975 to 1979. No patient had lymph node involvement following axillary dissection (N−), and no adjuvant medical treatment was given. Patients were classified in one of two groups according to the median LI. Patient … WebbThe thymidine labeling index (TLI) showed a lognormal distribution for 133 primary breast carcinomas, and the data suggested an association of high TLI with large primary tumor and the presence of axillary metastasis. 129 PDF Labeling index as a prognostic marker in non-Hodgkin's lymphomas. pinebrook allentown pa https://aweb2see.com

Proliferative index of breast carcinoma by thymidine labeling ...

WebbThe thymidine labeling index (TLI) showed significantly higher median values in the cancer patients (3.48 per cent) than in the patients with benign diseases (1.02 per cent). TLI … Webb1 jan. 1989 · Thymidine labeling index (TLI) and Ki-67 growth fraction (KGF) are two indicators of proliferative activity in breast cancer. The authors examined the relationship between TLI and KGF in 36 breast lesions (28 invasive ductal carcinomas and 8 … WebbIn contrast, when mice were given 17 repeated injections of 3H-thymidine at 6 hr intervals and killed 48 hr after the last injection, labeling indices in sialoadenectomized mice were significantly lower than those in sham-operated mice (35.3 +/- 4.3% vs 52.8 +/- 1.1% in the fundic gland area; 41.0 +/- 6.2% vs 55.1 +/- 5.9% in the pyloric gland ... top played games in the world

Thymidine - an overview ScienceDirect Topics

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Thymidine labeling index

Prognostic and predictive value of thymidine labelling index

Webb1 apr. 2000 · Quantitative evaluations of thymidine labeling of control, DHT-treated, or DHT plus flutamide–treated lungs were made by determining the labeling index of the airway epithelium and of the... Webb1 feb. 2001 · For thymidine labeling index and Ki-67, respectively, significant correlations existed with histologic tumour grade and steroid hormone receptors (Tumor grade: TLI p = 0.0001; Ki-67 p = 0.0001. ER ...

Thymidine labeling index

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Webb38 specimens of benign breast tissue from young women and 92 primary breast carcinomas were evaluated for tritiated thymidine ([3H]TdR) labeling index (TLI) by in … Webb3 H-Thymidine Labeling Index. 3 H-thymidine labeling index (TLI) was one of the first markers of proliferation used in breast cancer. The number of cells undergoing DNA …

Webb26 maj 2024 · Rapidly proliferating tumors were defined by thymidine labeling index (TLI) > 3% or histological grade 3 or S-phase > 10% or Ki67 > 20%. We analyze the subgroup of 466 patients with hormone receptor (HR)-positive tumors treated with sequential epirubicin/CMF regimens followed by tamoxifen and for whom immunohistochemical … WebbThymidine labeling index analysis in early breast cancer patients randomized to receive perioperative chemotherapy. TLI may be a useful tool for the identification of node …

WebbIN VITRO DETERMINATION OF TRITIATED THYMIDINE LABEIJNG INDEX (LI) Evaluation of a Method Utilizing Hyperbaric Oxygen and Observations on the LI of Human Mammary Carcinoma JOHN S. MEYER, MD,* AND WALTER C. BAUER, MD~ A simple method for incubation of tissue specimens with tritiated thymidine under 3 atm oxygen tension gave … WebbThe strong correlation between TLI and KGF in breast carcinoma suggests that KGF may have prognostic implications similar to those of the TLI, and in separately labeled benign breast tissue there was no significant correlation. Thymidine labeling index (TLI) and Ki-67 growth fraction (KGF) are two indicators of proliferative activity in breast cancer.

WebbOf all the older techniques, however, the most important, by far, is the thymidine labeling index (TLI). 5 Here viable cells are exposed briefly in vitro to a radiolabeled precursor of DNA. The most common thymidine …

Webb13 maj 2005 · Proliferation index was evaluated prospectively by deoxyribose nucleic acid precursor uptake with thymidine (autoradiographic) or bromodeoxyuridine (immunohistochemical) labeling index... pinebrook apartments bakersfield caWebbThymidine labeling index (TLI), which is a kinetic parameter showing tumor aggressivity and cell proliferation rate, is shown among the secondary group of prognostic factors for breast cancer, and appears to be independent of the known prognostic Factors. Abstract: In addition to primary prognostic factors (tumor size, axillary lymph node status, … top played games nowWebbThe data suggested, but did not prove, that a high LI was associated with more frequent metastasis to axillary lymph nodes, and it was suggested that the larger tumors were faster‐growing at the time of observation than the smaller tumors. A simple method for incubation of tissue specimens with tritiated thymidine under 3 atm oxygen tension gave … top played free games