Palytoxin, PTX or PLTX is an intense vasoconstrictor, and is considered to be one of the most poisonous non-protein substances known, second only to maitotoxin in terms of toxicity in mice. Palytoxin is a polyhydroxylated and partially unsaturated compound (8 double bonds) with a long carbon chain. It has … Prikaži več Legend According to an ancient Hawaiian legend, on the island of Maui near the harbor of Hana there was a village of fishermen haunted by a curse. Upon their return from the sea, one of the … Prikaži več Some of the organisms that contain palytoxin or its close analogues are listed below. These are either able to produce these compounds … Prikaži več From intravenous (IV) animal studies the toxic dose (LD50) of palytoxin via IV for humans has been estimated by extrapolation to be between 2.3–31.5 micrograms (µg) … Prikaži več There is no antidote for palytoxin. Only the symptoms can be alleviated. Animal studies have shown that vasodilators, such as papaverine and isosorbide dinitrate, … Prikaži več The toxicity of palytoxin is due to its binding to external part of Na /K -ATPase (the sodium–potassium pump), where it interacts with the natural binding site of ouabain with … Prikaži več The symptoms of palytoxin poisoning and how quickly they appear depend partially on how much and through what route one has been exposed, e.g. if the poison has been inhaled or if … Prikaži več Ingestion There have been cases where people died after eating foods containing palytoxin or poisons similar to it. In the Philippines people died after … Prikaži več Splet19. feb. 2024 · Palytoxin is a high–molecular mass fatty polyalcohol produced by zoanthid corals of the genus Palythoa. It is one of the most toxic nonprotein compounds known and contains one of the longest carbon chain of all naturally occurring molecules. In 1971, Richard E. Moore and Paul.
The mechanism of action and treatment of palytoxin poisoning
Splet15. dec. 2009 · Abstract. The EFSA Panel on Contaminants in the Food Chain (CONTAM Panel) assessed the risks to human health related to the presence of palytoxin (PlTX) … Splet22. okt. 2015 · Palytoxin is a very large, non-proteinaceous molecule with a complex chemical structure having both lipophilic and hydrophilic moieties. Palytoxin is one of the … theatro login page
Palytoxin Found in Palythoa sp. Zoanthids (Anthozoa ... - PLOS
SpletPalytoxin induces a relatively non-selective cation permeability in frog sciatic nerve which can be inhibited by cardiac glycosides. Toxicon 1988, 26 (10) , 941-951. Splet14. avg. 2015 · Inhalational exposure to palytoxin is an extremely rare cause of respiratory distress. This little-known marine toxin has the potential to cause significant morbidity and mortality. Toxicity has been … SpletPalytoxin C129H223N3O54 CID 4660115 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities ... theatro manager log in