Glucuronylation
WebFind changesets by keywords (author, files, the commit message), revision number or hash, or revset expression. WebO-glucuronylation will deactivate alpha-hydroxytamoxifen and compete with sulphonation. Rates of O-sulphonation of alpha-hydroxytamoxifen in hepatic cytosol have been determined by a HPLC assay of substrate-dependent 3'-phosphoadenosine 5'-phosphate production. The rank order of O-glucuronylation in hepatic microsomes was estimated by HPLC …
Glucuronylation
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WebMay 20, 2015 · The thermostable α-glucan phosphorylase-catalyzed enzymatic α-glucuronylation and subsequent α-glucosaminylation of glycogen using α-d-glucuronic acid 1-phosphate (GlcA-1-P) and α-d-glucosamine 1-phosphate (GlcN-1-P), respectively, produce amphoteric glycogens.The products exhibit the inherent isoelectric points, which …
WebDec 10, 2008 · Glucuronylation by a series of selectively O-acetylated glucuronyl bromides was studied to obtain the target products. It has been found that 3- O -acetylated donor 6 is the most efficient agent for α -glycoside bond formation that can be connected with intramolecular remote participation of 3- O -acetyl group favoring α-stereoselectivity. Webprotein amino acid glucuronylation; Definition: The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from …
Glucuronidation consists of transfer of the glucuronic acid component of uridine diphosphate glucuronic acid to a substrate by any of several types of UDP-glucuronosyltransferase. UDP-glucuronic acid (glucuronic acid linked via a glycosidic bond to uridine diphosphate) is an intermediate in the process … See more Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids. These linkages … See more Glucuronidation occurs mainly in the liver, although the enzyme responsible for its catalysis, UDP-glucuronyltransferase, has been found in all … See more WebMar 1, 2012 · Enzymatic α-glucuronylation was performed to give anionic oligosaccharides. Thermostable phosphorylase was used as a catalyst. Reaction of glucuronic acid 1-phosphate with maltooligosaccharides was conducted. Progress of α-glucuronylation was confirmed by MALDI-TOF MS and HPLC analyses. α …
WebDec 12, 2007 · Glucuronylation of neolactohexaose and lactose was also observed. The final glucuronylated oligosaccharides are precursors of the brain carbohydrate motif HNK-1, involved in neural cell adhesion. Escherichia coli, glucuronyltransferase, HNK-1, metabolic engineering, UDP-glucose dehydrogenase Issue Section: Communication Introduction
http://amigo.geneontology.org/amigo/term/GO:0018321 dallas college scheduleWebFeb 12, 2008 · Under these conditions, efficient glucuronylation of neolactotetraose was achieved, but some residual neolactotetraose was still present. Although E. coli K-12 has an indigenous UDP-glucose dehydrogenase, the yield of glucuronylated oligosaccharides was greatly improved by the additional expression of the orthologous gene kfiD from E. coli K5. dallas college radiology techWebFind changesets by keywords (author, files, the commit message), revision number or hash, or revset expression. marignane climatWebmethylation of k oxidation of m carboxymethyl c carbamidomethyl c deamidation of n and q propionamide c phosphorylation of s phosphorylation of t phosphorylation of y m cleavage from protein n-term acetylation of protein n-term methylation of protein n-term tri-methylation of protein n-term beta methythiolation of d methylation of q tri-methylation of k … dallas collegesWebFind changesets by keywords (author, files, the commit message), revision number or hash, or revset expression. marignane codeWebglucuronidation n. a metabolic process by which drugs or other substances are combined with glucuronic acid to form more water-soluble compounds, which are more readily excreted by the kidneys or in bile. Glucuronidation is the most prevalent of the Phase II reactions of drug metabolism. Browse Dictionary dallas college sign upWebMar 1, 2024 · The α- d -glucuronyl fluoride 2 and additive 5α-androstane-3β,17α-diol 3-glucuronide 3 mix was then added to the DHEA 1 and enzyme mix. Another four reactions were also set up by varying the final concentration of the additive 3 to 0, 5, 10, and 15 µM. dallas college semester dates