Foxm1 chip
WebMar 16, 2009 · To further validate these ChIP fractions, known FOXM1 transcriptional targets such as cyclin B1 (Supplemental Fig. S8A) and VEGF (Supplemental Fig. S8B–C) showed significantly higher copy numbers of respective promoters in the anti-FOXM1 ChIP fractions. FOXM1 did not bind to the promoter of the tumour suppressor p16 (CDKN2A; … WebJan 23, 2024 · To confirm whether AURKA promoter was a direct FOXM1 target, we performed ChIP analysis in MDA-MB-231 cells and observed strong FOXM1 binding at the promoter region containing the FHRE but …
Foxm1 chip
Did you know?
WebAug 9, 2024 · c Input normalized SAT1 ChIP assay on U87MG shGFP and shSAT1 cells on the MELK, FOXM1, EZH2, BRCA1, and NUSAP1 promoters. Histone H3 ChIP is a positive control. Histone H3 ChIP is a … WebForkhead box M1 (FOXM1), also named as HNF-3, HFH-11 or Trident, belongs to a superfamily of Fox transcription factors. FOXM1 is strongly associated with cell proliferation, it plays a important role in cell cycle …
WebAug 12, 2015 · EMSA and ChIP assays confirmed that FoxM1 directly binds to PTTG1 promoter at the −391 to −385 bp region in colorectal cancer cells. Boyden chamber assay indicated that both FoxM1 and PTTG1 regulate migration and invasion of HCT116 and SW620 colorectal cancer cells. Further in vivo assays indicated that PTTG1 knock out … WebAug 21, 2011 · d, FOXM1 ChIP was performed on MCF-7 cells treated for four hours with either DMSO or 1 (10 µM). RT-PCR was performed to investigate binding events at some known and putative FOXM1 binding …
WebSep 12, 2024 · FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor that is widely spatiotemporally expressed during the cell cycle. It is closely involved with the processes of cell … WebJun 7, 2024 · FoxM1 is an oncogenic transcription factor that has been linked to the genesis and progression of cancer. FoxM1 not only upregulates cell proliferation and survival genes, but also represses tumor suppressor genes according to our prior study. This ChIP-Seq is a part of our endeveavor to creat a map of the FoxM1 occupied chromatin area in order ...
WebOct 5, 2024 · FoxM1 promotes the migration of ovarian cancer cell through KRT5 and KRT7 Authors Ziyu Zhang 1 , Kaijia Tu 2 , Faying Liu 1 , Meirong Liang 2 , Kaihui Yu 3 , …
WebAug 16, 2024 · As a transcription factor, FOXM1 binds to its specific binding sites in the promoters or enhancers of its target genes and regulates their transcription. In the TRANSFAC 2.0 database, there are five positional weight matrices for FOXM1, either built from individual genomic binding sites or based on a ChIP-seq dataset. The core binding … shorter university websiteWebFOXM1 belongs to a large family of Forkhead transcription factors that possesses a winged-helix DNA-binding domain called Forkhead box … san francisco muni shootingWebTo test whether homologous recombination repair (HRR) depends on FOXO3a, a cellular aging model of human dermal fibroblast (HDF) and tet-on flag-h-FOXO3a transgenic mice were studied. HDF cells transfected with over-expression of wt-h-FOXO3a increased the protein levels of MRE11, BRCA1, BRIP1, and RAD50, while knock-down with siFOXO3a … shorter updateWebFOXM1 (forkhead box protein M1) is a transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. FOXM1 plays a role in the control … shorter university women\u0027s volleyballWebOct 12, 2024 · FOXM1 CHIP. FOXM1 binding sites in the LDHA promoter have been described previously (Cui et al., 2014). Cells were washed with phosphate-buffered saline (PBS) and crosslinked with 1% formaldehyde for 10 min at 37 °C. The reaction was stopped by the addition of glycine to 125 mM final concentration. Samples were sonicated to … shorter university women basketballWebMar 9, 2024 · FOXM1 Antibody (G-5) is an IgG 2b κ mouse monoclonal FOXM1 antibody (also designated HNF3 antibody, FKHL16 antibody, forkhead box M1 antibody) that detects the FOXM1 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. FOXM1 Antibody (G-5) is available as both the non-conjugated anti-FOXM1 antibody … san francisco motels hotelsWebMar 21, 2024 · FOXM1 (Forkhead Box M1) is a Protein Coding gene. Diseases associated with FOXM1 include Hepatocellular Carcinoma and Protein C Deficiency. Among its related pathways are Loss of Nlp from mitotic centrosomes and Cell Cycle, Mitotic. ... Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FOXM1 shorter university volleyball roster