Dynein light chain roadblock-type 1
WebAug 14, 2024 · Here, we report NAGK interacts with dynein light chain roadblock type 1 (DYNLRB1) and efficiently suppresses mutant huntingtin (mHtt) (Q74) and α-synuclein … WebMay 20, 2024 · Dynein is a multi-subunit nanomotor built around a core of large dimeric heavy chains (HCs), which perform ATP hydrolysis to power motion and provide a …
Dynein light chain roadblock-type 1
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Webchain roadblock type 1 (DYNLRB1)11 to promote dynein functions during mitosis12 and axonal13 and dendritic growth14,15.In the present study, we asked whether NAGK also … WebAug 14, 2024 · Here, we report NAGK interacts with dynein light chain roadblock type 1 (DYNLRB1) and efficiently suppresses mutant huntingtin (mHtt) (Q74) and α-synuclein (α …
WebMar 27, 2024 · Dynein is composed of four subunit classes: the heavy chain (HC), light intermediate chain (LIC), intermediate chain (IC), and light chain (LC) (Fig. 1a). The HC has both ATPase and MT-binding activities and thus functions as the motor domain3–5. The LICs serve as a major binding interface for cargo-adaptor proteins6. WebOur work demonstrates that two distinct dynein complexes containing DYNLRB1 or DYNLRB2 are separately used in mitotic and meiotic spindle formations, respectively, and that both have NuMA as a common target.© 2024. The Author (s). Links http://www.ncbi.nlm.nih.gov/pubmed/36973253 http://dx.doi.org/10.1038/s41467-023 …
WebDynein is the primary minus-end-directed microtubule motor. To achieve activation, dynein binds to the dynactin complex and an adaptor to form the "activated dynein complex". The protein Lis1... WebApr 1, 2004 · The Roadblock/LC7 class of light chains associate with the intermediate chains at the base of the soluble dynein particle. In mammals, there are two Roadblock isoforms (Robl1 and Robl2), one of which (Robl2) is differentially expressed in a tissue-dependent manner and is especially prominent in testis.
WebDynlrb1 dynein light chain roadblock-type 1 [ (Norway rat)] Gene ID: 170714, updated on 21-Dec-2024 Summary Predicted to enable dynein intermediate chain binding activity …
WebNov 1, 2000 · The Roadblock light chains are ubiquitous components of cytoplasmic dynein that form homo- and heterodimers. Karina Nikulina, R. Patel-King, S. Takebe, K. Pfister, S. King Biology Cell motility and the cytoskeleton 2004 TLDR imitrex and tylenol interactionWebSymbol Description Category UniProt ID GIFtS GC id Score; 3826: DAPP1: Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides 1: Protein Coding: Q9UN19: 44: GC04P099816 list of roller coasters at universal orlandoWebDYNLRB1 is essential for dynein mediated transport and neuronal survival Authors Marco Terenzio 1 , Agostina Di Pizio 2 , Ida Rishal 2 , Letizia Marvaldi 2 , Pierluigi Di Matteo 2 , … list of roman catholic saints namesWeb5,351 transcription cofactor Silencer Select Pre-designed, Validated, and Custom siRNA in Standard, HPLC, and In-vivo Ready Purities. list of romance booksWebThe .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. imitrex and sulfa allergyWebSep 6, 2024 · This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts … imitrex and strokeWebNX_Q9NP97 - DYNLRB1 - Dynein light chain roadblock-type 1 - Interactions. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that … imitrex and trazodone interaction