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Cytoskeleton-associated protein 4

WebJul 8, 2024 · Synaptic activity mediates information storage and memory consolidation in the brain and requires a fast de novo synthesis of mRNAs in the nucleus and proteins in synapses. Intracellular localization of a protein can be achieved by mRNA trafficking and localized translation. Activity-regulated cytoskeleton-associated protein (Arc) is a … WebMar 21, 2024 · Cytoskeleton-associated protein 4 (CKAP4) promotes malignant progression of human gliomas through inhibition of the Hippo signaling pathway. …

Cytoskeleton-Associated Protein 4, a Promising Biomarker …

WebCytoskeleton-associated protein 4 (CKAP4) is also known as p63 and cytoskeleton-linking membrane protein 63kDa (CLIMP-63). It was first described as a palmitoylated single-pass transmembrane receptor that localized to the rough endoplasmic reticulum as well as the cell membrane. WebCytoskeleton-associated protein 4 (CKAP4) is a non-glycosylated type II transmembrane protein that serves as a cell surface-activated receptor. It is expressed primarily in … openoffice*$ https://aweb2see.com

SARS-CoV-2 Spike protein promotes vWF secretion and …

WebEdges represent protein-protein associations associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other. Known Interactions from curated databases experimentally determined Predicted Interactions gene neighborhood gene fusions WebJul 21, 2024 · Since then, various components of the cytoskeleton network have been shown to be involved in virtually all steps of the viral life cycle. For example, numerous viruses have been found to re-organize actin structures near the plasma membrane to facilitate endocytosis-mediated viral entry [ 2, 3, 4 ]. Once inside the cell, many viruses … WebOct 31, 2012 · Cytoskeleton-associated protein 4 (CKAP4; also known as p63, CLIMP-63, or ERGIC-63) is a 63 kDa, reversibly palmitoylated and phosphorylated, type II transmembrane (TM) protein, originally identified as a resident of the endoplasmic reticulum (ER)/Golgi intermediate compartment (ERGIC). openoffice 2019 download deutsch

Cytoskeleton-Associated Protein 4 Is a Novel

Category:Prognostic significance of cytoskeleton‐associated membrane …

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Cytoskeleton-associated protein 4

mRNA Trafficking in the Nervous System: A Key Mechanism of the ...

WebAug 7, 2024 · Regenerative medicine represented by stem cell technology has become one of the pillar medical technologies for human disease treatment. Cytoskeleton plays important roles in maintaining cell morphology, bearing external forces, and maintaining the effectiveness of cell internal structure, among which cytoskeleton related proteins are … WebAug 21, 2024 · The cytoskeleton is a network of fibers forming the "infrastructure" of eukaryotic cells, prokaryotic cells, and archaeans. In eukaryotic cells, these fibers consist of a complex mesh of protein …

Cytoskeleton-associated protein 4

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WebMay 17, 2024 · CKAP4 (cytoskeleton‐associated protein 4) is a DKK1 binding protein expressed on the surface of cells, with DKK1/CKAP4 promoting pancreatic cancer and lung cancer . DKK1 is considered a factor that can modulate the β‐catenin pathway and stimulate cancer cells or noncancerous proliferation [61, 62]. Zyxin localizes to focal adhesion sites ... WebOct 25, 2010 · Deep sequencing of mutant DNA revealed a mutation located in an intron of the Mtap2 gene, encoding microtubule-associated protein 2, and levels of Mtap2 transcript were reduced in mutant testes. ... Together, these and other as yet unknown regulators bring about progressive changes in the nucleus and cytoskeleton, including desynapsis, ...

WebOct 31, 2012 · Abstract and Figures. Cytoskeleton-associated protein 4 (CKAP4; also known as p63, CLIMP-63, or ERGIC-63) is a 63 kDa, reversibly palmitoylated and … WebApr 14, 2024 · Searching to explain certain pathogenic mechanisms associated with subependymal and subcortical heterotopia, the authors provide evidence that Dlgap4 interacts with proteins mediating VS integrity, influences the F-actin cytoskeleton, as 10 well as progenitor dynamics and proliferation.

WebSep 19, 2024 · Cytoskeleton-associated protein 4 (CKAP4; also known as p63, CLIMP-63, or ERGIC-63) is a 63 kDa, reversibly palmitoylated and phosphorylated, type II transmembrane (TM) protein, originally identified as a resident of the endoplasmic reticulum (ER)/Golgi intermediate compartment (ERGIC).

WebJun 1, 2024 · CKAP4 is a 63-kDa non-glycosylated and reversibly palmitoylated type II transmembrane protein that has been shown to anchor rough endoplasmic reticulum and microtubules in epithelial cells.5 Although CKAP4 was described as an endoplasmic reticulum–resident protein, it is also now known to be expressed on the surface of …

WebSep 1, 2013 · Cytoskeleton-associated membrane protein 4 (CKAP4), one kind of type II trans-membrane protein, mainly located in the endoplasmic reticulum [11], [12]. … ipad league of legendsWebApr 7, 2015 · cytoskeleton-linking membrane protein (CLIMP-63)/ cytoskeleton-associated protein 4 (CKAP4), palmitoyl-acyltransferase 2 (has a DHHC motif) [DHHC2], endoplasmic reticulum (ER) cytoskeleton anchor, nuclear translocation, palmitoylation, plasma membrane receptor, rough endoplasmic reticulum (RER) ipad latest version priceWebSep 2, 2024 · CKAP4 expression is associated with tumor grade in gliomas. Quantification of CKAP4 expression using RNA sequencing data from A GEPIA and B CGGA … ipad latest model best buyWebFeb 25, 2024 · They applied it for the first time to the intestine and identified regenerating islet-derived protein 4 ( Reg4) as a novel marker for enteroendocrine cells, a rare population of hormone-producing intestinal cells [ 32 ]. Regenerative properties of the adult mammalian heart are insufficient to repair the heart post-ischemic injury. open office 365 anmeldenCKAP4 as a receptor of APF plays an important role in mediating bladder carcinoma cells proliferation. Following CKAP4 knockdown, the inhibition effect of APF on T24 cell proliferation was eliminated, indicating the important role of the receptor in mediating the antiproliferation activity of APF in bladder cancer … See more Our group investigated the relationship between CKAP4/DHHC2 expression and prognosis in 416 patients with hepatocellular carcinoma (HCC) (Li et al., 2014b) (Table 2). … See more Previous studies reported that CKAP4 as an ER enriched protein could be secreted by exosomes of ovarian and colon cancer cells and detected as an exosomal protein in urine (Gonzales et al., 2009; Demory Beckler et al., 2013; … See more Although plentiful researches focused on the relationship between CKAP4 and cancer, there were also studies that showed that CKAP4 played an important role in noncancers. … See more Sufficient studies have confirmed that CKAP4 correlated with various cancers’ progress and prognosis. The formation of the xenograft tumors derived from CKAP4-depleted cells, including lung cancer cells (Kimura et al., 2016), … See more open office 365 inloggenWebAug 21, 2012 · Cytoskeleton-associated protein 4 (CKAP4; also known as p63, CLIMP-63, or ERGIC-63) is a 63 kDa, reversibly palmitoylated … openoffice 2 seite entfernenWebSep 4, 2009 · Palladin is an actin cytoskeleton–associated protein which is crucial for cell morphogenesis and motility. Previous studies have shown that palladin is localized to the axonal growth cone in neurons and may play an important role in axonal extension. Previously, we have generated palladin knockout mice which display cranial neural tube … ipad latest generation how much