IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. Constitutive expression of IRF7 is largely restricted to lymphoid tissue, largely plasmacytoid dendritic cells, whereas IRF7 is inducible in many tissues. Multiple IRF7 tr… WebJul 25, 2024 · The primary antibodies were RIG-I polyclonal antibody (CST, United States), anti-Phospho-IRF7 (Bioss, China), GAPDH (Abcam, United States), Rabbit Anti-ASC antibody (Proteintech, United States), cleaved …
Activation of interferon regulatory factor 7 in …
WebOct 3, 2024 · Cell Signaling Technology IRF7 antibody (Cell Signaling, 4920) was used in western blot knockout validation on human samples (fig 3a). MBio (2024) ncbi Santa Cruz Biotechnology BioLegend mouse monoclonal (12G9A36) 656008 flow cytometry; human; loading ...; fig 2d WebJan 10, 2024 · The essential role of IRF7 in the human type I IFN cascade is illustrated by the fact that IRF7 deficiency caused by homozygous loss-of-function variants is linked to life-threatening influenza in ... dgm 4054 1710 block learning navy
Phospho-IRF7 (Ser471, Ser472) Polyclonal Antibody
WebApr 7, 2005 · Consistently, Irf7-/- mice are more vulnerable than Myd88-/- mice to viral infection, and this correlates with a marked decrease in serum IFN levels, indicating the … Web53 minutes ago · TLR7 signaling, via the adaptor protein MyD88, activates IRF7 and NF-κB, ... MSCs in mice models 6 h after lung injury caused by intratracheal administration of bleomycin increased G-CSF and GM-CST levels in circulation and reduced inflammatory cytokines. Furthermore, Maron-Gutierrez et al. ... WebOct 10, 2014 · Interferon regulatory factor 7 ( IRF 7), a member of the interferon regulatory factor family, plays important roles in innate immunity and immune cell differentiation. However, the role of IRF 7 in … dgm 4054 1710 block learning