웹Bak protein interacts with TUMOR SUPPRESSOR PROTEIN P53 and promotes APOPTOSIS. Skip to search form Skip to main content Skip to account menu. Semantic … 웹2013년 2월 12일 · In contrast to BAK, BAX resides in the cytosol as an inactive monomer until stimulated to translocate to the mitochondria and self-associate to form pores. Select …
Research Paper Discovery of Small Molecule Bak Activator for …
웹Description: Homo sapiens BCL2 antagonist/killer 1 (BAK1), mRNA. (from RefSeq NM_001188) RefSeq Summary (NM_001188): The protein encoded by this gene belongs … 웹2011년 9월 14일 · Low Bak protein in resistant cells and Bak-dependent apoptosis induced by immunotoxin. A, Western blotting after SS1P-KDEL treatment for 24 hours. B, Bak and Bax expression in lentiviral infected stable Bak KB31 clones detected with Western blotting, and compared with the same amount of KB31, empty lentiviral infected KB31 (control), and 2 … reflectors part 393
Molecular Determinants for the Activation/Inhibition of Bak …
http://www.bjbalb.com/html/Primary-Antibody/YT647.html 웹BAK1. 该基因编码的蛋白属于BCL2蛋白家族bcl2家族成员形成寡聚体或异二聚体，作为抗或促凋亡的调节因子，参与多种细胞活动。. 该蛋白定位于线粒体，具有诱导细胞凋亡的功能。. … BAK1 is a pro-apoptotic Bcl-2 protein containing four Bcl-2 homology (BH) domains: BH1, BH2, BH3, and BH4. These domains are composed of nine α-helices, with a hydrophobic α-helix core surrounded by amphipathic helices and a transmembrane C-terminal α-helix anchored to the mitochondrial … 더 보기 Bcl-2 homologous antagonist/killer is a protein that in humans is encoded by the BAK1 gene on chromosome 6. The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or … 더 보기 As a member of the BCL2 protein family, BAK1 functions as a pro-apoptotic regulator involved in a wide variety of cellular activities. In healthy mammalian cells, BAK1 localizes … 더 보기 BAK1 has been shown to interact with: • BCL2-like 1, • Bcl-2, • MCL1, 더 보기 • Human BAK1 genome location and BAK1 gene details page in the UCSC Genome Browser. 더 보기 Generally, the pro-apoptotic function of BAK1 contributes to neurodegenerative and autoimmune diseases when overexpressed and … 더 보기 • Buytaert E, Callewaert G, Vandenheede JR, Agostinis P (2007). "Deficiency in apoptotic effectors Bax and Bak reveals an autophagic cell death pathway initiated by photodamage to the endoplasmic reticulum". Autophagy. 2 (3): 238–40. doi:10.4161/auto.2730 더 보기 reflectors over lisense plate